2024-11-11 Westbrook/Wagner Check-in meeting notes

Participants

  • @Brent Westbrook

  • @Jeffrey Wagner

Discussion topics

Item

Notes

Item

Notes

 

  • JW –

    • Made QCSubmit and Bespokefit releases, let me know if there’s any trouble.

      • BW – Already used new QCSubmit to submit a new dataset, should fix the old issue once it goes through.

    • LipidMaps workers seem to be slowing down

      • BW – Unsure what’s going wrong here. Have two types of workers submitted. I went in using an interactive shell and saw lots of psi4 jobs completing but may be finite difference inner steps or something.

      • JW – I wonder if we get hammered by molecule size when doing hessians since it scales quadratically

      • BW – I think for the opt steps it should just be doing gradient, so 3N rather than 3N^2

      • JW – Maybe just try workers with a lot more resources? Could deploy just a few high-resource workers, up to 32 cores and 64GB ram. Try exploring the parameter space under that.

      • BW – Sounds good, I tried doing parameter sweeps with a script last week. Weird because AMI said (and I saw in logs) that even large-ish mols should nly need 5-10GB of RAM. But this may scale with number of cores as well.

      • JW – Could also look at n_opt_steps as a funciton of molecule size?

      • BW – Yeah, could look at the length of opt trajectory for finished jobs.

      • …

      • BW – I’ll try some of these things, and if it still doesn’t unblock the set I’ll split by size

      • JW – Sounds good.

  • BW – Rocket dataset is finished. I told CAdams, seems like there was something wrong with their infra. Moved to scientific review and am awaiting feedback from CAdams.

    • JW – Great, well handled.

Trello

https://trello.com/b/dzvFZnv4/infrastructure

Action items

Decisions

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