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\uD83D\uDDD3 Date

\uD83D\uDC65 Participants

\uD83D\uDDE3 Discussion topics

Item

Notes

Updates from MolSSI

  • (BP not in attendance)

Infrastructure advances

  • (None to discuss)

Throughput status

  1. OpenFF Protein Capped 3-mer Backbones v1.0

    • Opts: 262844 → 264954

    • TDs: 5 → 6

  2. RNA Single Point Dataset v1.0

    • default: 8864 → 8868 (100 error)

    • wb97m-d3bj/def2-tzvppd: still stuck at 3468 with 950+ incomplete jobs. Submitted fat node jobs (48 cores/240 GB/ 500GB scratch) on UCI cluster to get this out but all are QCEngine unknown failures.

    • PB – I’ll try one of these failing jobs locally and watch it closely. Not sure whether it’s resource requirements or something else.

  3. SPICE sets with openff-default spec

    • MBIS errors with Iodine containing molecules seems suspicious

        • In code:

        • /* Updated parameters for initial MBIS params Nai and 1/Sai
             (from https://github.com/theochem/denspart/blob/740449c375f7e1c7b14cc8a978a8d0b1ed4617e3/denspart/mbis.py#L82 by Toon
             Verstraelen) */
          // Attention: MBIS is not supported for elements with atomic number greater than 36
      • Fatal Error: Atomic Number 53 unsupported by MBIS

      • PB – I’m confused, since we’ve previously done sets using Iodine.

      • DD – Do we not ask for MBIS charges in our default level of theory?

        • PB – It looks like we DON’T have MBIS set in our default, but we ARE requesting MBIS in SPICE. But MBIS doesn’t work for Iodine.

        • DD – Does method and basis interact with MBIS?

        • PB – Maybe.

        • DD – We’d worked with the psi4 devs before about this, right?

        • PB – Yeah, they has auxilliary basis for stuff up to Bromine, and after talking to us they added it up to iodine.

        • PB – I’ll bring this us with psi4 devs.

    • Complete

      • SPICE Solvated Amino acids

    • Moved to end of life:

      • SPICE DES370K Single Points Dataset v1.0

      • SPICE DES Monomers Single Points Dataset v1.1

      • SPICE Ion Pair

      • SPICE Dipeptides Single Points Dataset v1.2

      • SPICE Pubchem sets 1,2, (3)

    • In queue (being computed):

      • SPICE Pubchem set 4,5,6

User questions/issues

  • DD: Node allotment?

    • PB – The current mix looks good. We have the SPICE sets going through and the current number+size of nodes look good.

  • CC: Geometric release?

    • JW – I’ll be running a forcebalance release soon. So I’ll be in contact with LPW. Could push on this. It’s not at the top of my to-do list so it may be >1 week out. Is that OK?

    • PB + CC – Yes.

  • DD – Currently can’t submit jobs on MPI cluster. I’ll work with sysadmins to figure out why. They were of limited use anyway because the nodes didn’t have a ton of scratch space. These were consuming jobs from openff-uci and openff-tscc labels. 3mers are on the TSCC tag, uci tag doesn’t have any active sets right now.

Science support needs

✅ Action items

  •  

⤴ Decisions

  • No labels