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  • whether this is a good choice for charged molecules?

  • any density-driven or delocalization errors creep up in torsion scans as shown in Burke’s papers (https://dx.doi.org/10.1021/acs.jpclett.1c00426 )

  • how good it is in describing problematic chemistries, like

    • biaryl torsion barriers (http://dx.doi.org/10.1021/ct5004725 ).

    • chalcogen, halogen interactions (http://doi.org/10.1021/acs.jctc.1c00006 ). Strong polarizability from these elements induce strong dispersion interactions, and there is a need to check on how the current level of theory is performing and whether the dispersion corrections are good enough to compensate for that.

    • and non covalent interactions in general.

  • transferability of accuracy shown in density functional benchmarks with larger basis sets (from literature) to smaller basis sets?

Scope

Must have:

  • Accuracy of torsional profiles, accuracy of dipole and quadrupole moments, comparison of computational performance of methods

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