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Initial values

td+opt+vib

opt

vib freq

td

td+opt

td+opt+vib + child

Frostt99

1

2

3

4

5

6

a30, angle

109.5

113.0

108.9

115.9

109.9

113.1

113.0

a30, k

140.0

150.0

171.1

166.9

95.4

139.7

172.2

a31, angle

109.5

107.5

101.1

114.0

111.4

107.5

110.4

a31, k

120.0

122.1

153.5

204.2

37.0

117.7

115.9

a30b, angle

125.0






123.5

a30b, k

140.0






189.7

run status

complete

complete

complete

complete

complete

complete

*angle in degrees, k in kcal/mol/rad^2

Comparison of opt only targets' fits with change in forcebalance options

L2 penalty on the objective function for regularization.

penalty_additive: Factor for additive penalty function in objective function. Add a penalty to the objective function (e.g. L2 or L1 norm) with this prefactor. Using an additive penalty requires an assessment of the order of magnitude of the objective function, but it is closer to the
statistical concept of ridge or LASSO regression.

penalty_multiplicative: Factor for multiplicative penalty function in objective function.
Multiply the objective function by (1+X) where X is this value. Using an multiplicative penalty
works well for objective functions of any size but it is not equivalent to statistical regularization methods.

use_pvals: Bypass the transformation matrix (mvals) and use the physical parameters directly


Initial values
Frostt99

#2 in above table

(default option of
1.2.0 fit)




penalty_additive 1.0

penalty_additive 0.0 penalty_multiplicative -1.0

penalty_additive 0.0 penalty_multiplicative -1.0 use_pvals true

a30, angle

109.5

108.9

112.5

-3.66E-04

a30, k

140.0

171.1

150.6

-4.62E-03

a31, angle

109.5

101.1

105.6

4.26E-04

a31, k

120.0

153.5

123.6

7.75E-05